Life for 50 year old Alice is fine. She has husband (Baldwin), grown children and is good at her job. But then one day she loses her thread, and is diagnosed with early-onset Alzheimer’s.

Based on Lisa Genova’s novel, Julianne Moore delivers a delicate, award-winning performance, slowly revealing Alice’s gradual erosion of memory and loss of confidence that comes with her cruel decline.

Directors Richards Glatzer (himself suffering from a neurodegenerative condition) and Wash Westmoreland tackle a difficult subject with bravery.